Go Goa Gone story is about Hardik (Kunal Khemu) and Luv (Vir Das) are two dope heads, slackers, stuck in dead-end jobs. Thank God for drugs, drinks and Goa (India’s party destination). Girls are, of course, a welcome bonus. They hijack their best buddy Bunny (Anand Tiwari) on his way to work, so he can pay for the trip. Luv comes across Luna (Puja Gupta), a beautiful, free-spirited girl, and she casually invites him to exactly what they are looking for – an exclusive underground rave party on a remote island! The party is the brainchild of the macho Russian Mafioso, Boris (Saif Ali Khan), to launch the ultimate drug. But something is wrong, very wrong, on this island! All of a sudden, they are accosted by these people? Creatures? Things? Where are all the party people? Who are these things? And why are they out to kill them? And who is Boris? And why has this cold-hearted drug-dealing don come to save their lives? forms rest of the story.