Raja Meeru Keka story is about Ravi(Revanth), Swetha (Lasya), Shashank(Noel) and Seenu(Hemanth) are four best friends who are happy with their respective jobs. One fine day, a person named Nagaraju(Tarak Ratna) who owns an MNC enters the scene and creates a big disturbance in the lives of these four friends. What is that disturbance? How are Nagaraju and these four friends connected? How do these friends solve their problems? That forms the rest of the story.